Using Layers

I am using the layers functionality in the Clip Editor to create variations of a single base animation. My base animation clip has 5 layers on it that modify the movement of some bones to add variety to the original motion. I would like to be able to Mute and un-Mute layers from my script.

My current workflow is to duplicate the current clip (with all the layers), then mute the specific layers differently on the different duplicate clips, then export them to create 5 modified animations. However, if I need to modify the base animation clip I have to delete all the duplicate clips, then re-duplicate them from the base clip, then mute the specific layers differently, then re-export them as separate animations.

Is there a way to mute and un-mute layers from script? If not is there a less manual workflow for creating many animations?

Thank you for the help!